SkinCeuticals A.G.E. Interrupter Advanced


A.G.E. Interrupter Advanced is a corrective anti-ageing cream that helps target visible signs of ageing caused by advanced glycation end products (A.G.E), including wrinkles, skin firmness and dullness.

This next-generation anti-glycation, anti-wrinkle cream is formulated with 12.6% concentrated Proxylane (+20% more than previous A.G.E. Interrupter), 4.25% wild fruit flavonoid blend (12.5% more), and new 0.1% glycyrrhetinic acid. The A.G.E Interrupter Advanced technology is shown to minimise visible wrinkles and help counteract the loss of firmness caused by the glycation process. Learn more on how to create an everyday anti-ageing skincare routine for mature skin.

SKIN TYPES: Dry, Normal, Combination, Sensitive


  • This A.G.E Interrupter Advanced is a collagen boosting cream that includes niacinamide & proxylane to help stimulate collagen production, address wrinkles and elasticity of the skin.
  • Using this anti-wrinkle cream helps to smooth out deep wrinkles, fine lines, and location-specific creases like nasolabial folds while enhancing overall skin radiance and improves skin tone for a healthier-looking complexion.
  • The A.G.E Interrupter Advanced is an anti-glycation cream that helps address the glycation process effecting collagen and elastin protein in the skin, in turn helping restore skins firmness and elasticity.
  • Suitable for ageing and dry skin. The A.G.E Interrupter Advanced supports the skin moisture barrier and hyaluronic acid synthesis in the skin for hydration.
  • Free of parabens, drying alcohol, and dyes.


Twice daily, start by cleansing the face with the SkinCeuticals Glycolic Renewal Foaming Facial Cleanser. Massage a thin, even layer of the A.G.E. Interrupter Advanced anti-wrinkle cream.

For best results, use the anti-wrinkle cream in the morning after applying the SkinCeuticals CE Ferulic Vitamin C Serum and finish your skincare routine with the SkinCeuticals Ultra Facial Defense SPF 50+ Sunscreen. If using with a retinol at night, apply after retinol application.


    • MORE CONCENTRATED PROXYLANE (+20% MORE THAN ITS PREDECESSOR, A.G.E. INTERRUPTER): Proxylane is a sugar protein hybrid derived from Xylose, a natural sugar. Proxylane helps stimulate collagen production to support skin’s integrity and correct visible signs of ageing, like wrinkles and laxity.
    • 4.25% WILD FRUIT FLAVONOIDS: Plant derived compounds or flavonoids are beneficial for their antioxidant properties. Flavonoids are also known to help with visible signs of ageing. A combination of blueberry and pomegranate extracts help reduce oxidative stress CB3:CD3s, which can be linked to A.G.E. formation, and protect against free radical damage.
    • 0.1% GLYCYRRHETINIC ACID: Glycyrrhetinic acid is one of the components of licorice, known for its ability to help calm skin and minimise feeling of sensitivity in skin. It also acts as an antioxidant, helping counter dull tone, which can be linked to A.G.E. accumulation, and is known for its soothing properties.
    • 3% HEPES: Sulfonic Acid or HEPES is known for its exfoliating properties by activating natural enzymes in skin to promote even cell turnover while hydrating skin. It is also known to reduce inflammation, addressing acne-prone skin concerns.


Topical niacinamide in skincare, also known as vitamin B3 has several antioxidant benefits while acting as a humectant that helps attract and retain moisture within the skin. Niacinamide is making it a great skincare ingredient for acne prone or sensitive skin types.


855355 100 Aqua / Water, Hydroxypropyl Tetrahydropyrantriol, Glycerin, Propylene Glycol, Stearic Acid, Butyrospermum Parkii Butter / Shea Butter, Hydroxyethylpiperazine Ethane Sulfonic Acid, Palmitic Acid, Pentylene Glycol, Oleyl Alcohol, Arachidyl Alcohol, Myristyl Myristate, Panthenol, Niacinamide, Dimethicone, Isononyl Isononanoate, Bis-peg/ppg-16/16 Peg/ppg-16/16 Dimethicone, Glyceryl Stearate, Candelilla Cera / Candelilla Wax, Behenyl Alcohol, Peg-100 Stearate, Sodium Polyacrylate, Pentaerythrityl Tetraisostearate, 4-t-butylcyclohexanol, Arachidyl Glucoside, Caprylyl Glycol, Xanthan Gum, Chlorphenesin, Myristic Acid, Caprylic/capric Triglyceride, Glycyrrhetinic Acid, Parfum / Fragrance, Sorbitol, Vaccinium Myrtillus Fruit Extract, Potassium Hydroxide, Adenosine, Citric Acid, Punica Granatum Fruit Extract, Limonene, Coumarin, Linalool, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate F.I.L N70022657/1


Free Shipping

Free Shipping For Orders Over $130

Big Saving

Big Saving On First Order Over $99.99

Online Support

24 Hours A Day, 7 Days A Week

Flexible Payment

Pay With Multiple Credit Cards